Superintendent

Dr. Hung Chi Chang

2002-2007 Total of 12 times, At the American Association of Reproductive Medicine annual speech

Resume

  • 1986-1993  Medical School of National Taiwan University, Taiwan.

  • 1995-1999  Resident Physician, Department of Obstetrics and Gynecology, Medical Center of National Taiwan University, Taiwan.

  • 1999-2001  Fellow of Reproductive Endocrinology, Department of Obstetrics and Gynecology,Medical Center of National Taiwan University, Taiwan.

  • 2001-2007  Research Scientist,Fertility center, Department of Obstetrics and Gynecology, New York University, USA.

  • 2008-2009  Taipei Veterans Gen. Hospital, Dept of Obstetrics and Gynecology

Research

 

Published in Molecular Biology of the Cell

  • Yi Liao, Hung-Chi Chang et al.(2018,Molecular Biology of the Cell) Uroplakins play conserved roles in egg fertilization and acquired additional urothelial functions during mammalian divergence.(10 Oct 2018) Download the research profile.

Cited by Nature

  • Jing Chen, Simona Torcia, Fang Xie, Chih-Jen Lin, Hakan Cakmak, Federica Franciosi, Kathleen Horner, Courtney Onodera, Jun S. Song, Marcelle I. Cedars, Miguel Ramalho-Santos, and Marco Conti.( 2013) Somatic cells regulate maternal mRNA translation and developmental competence of mouse oocytes. Nat Cell Biol. 2013 December ; 15(12): 1415–1423. doi:10.1038/ncb2873. Download the research profile.
  • Chang HC, Liu H, Zhang J, Grifo J, Krey LC. (2005). Developmental incompetency of denuded mouse oocytes undergoing maturation in vitro is ooplasmic in nature and is associated with aberrant Oct-4 expression. Hum Reprod , 1958–1968. Download the research profile.

  • Research

  • Chang HC, Grifo J, McCaffrey, Krey LC, Noyes N. (2007 ASRM) Using certain commercially available glass-bottomed dish with paraffin oil impacts the embryonic development of oocytes. [Abstract] Fertility & Sterility. 2007; 88: S310 (#J0130599).

  • Chang, HC; Liu, H; Noyes, N; Meng, L; Krey, L; Grifo, J. “Down regulatory effects of retinoid signaling on murine and human embryonic Oct-4 gene expression [Abstract]”. Fertility & sterility. 2006; 86: S219 (#J0123967)

  • Noyes, N; Chang, HC; Liu, H; Labella, P; Meng, L; Grifo, JA. “Presence of meiotic spindle predicts embryo competence following oocyte cryopreservation [Abstract]”. Fertility & Sterility. 2006; 86: S64 (#J0123958) Chang, HC; Noyes, N; Lee, TL; Chin, A; Krey, L; Grifo, J. “Independent and sequential expression of Oct3A and Oct3B transcription factors in human preimplantation embryos [Abstract]”. Fertility & Sterility. 2006; 86: S220 (#J0123968)

  • Chang, HC; Grifo, J; Labella, P; Ampeloquio, E; Adler, A; Krey, L. “Oct3A and Oct3B immunostaining patterns in human 3PN zygotes and aneuploid embryos diagnosed by preimplantation genetic diagnosis (PGD): Embryonic chromosome status can be independent of developmental competence [Abstract]”. Fertility & Sterility. 2006; 86: S220 (#J0123969)

  • Keegan DA, Krey LC, Chang HC and Noyes N. (2007) Increased risk of pregnancy-induced hypertension between in young recipients of oocyte donation. Fertility and Sterility. Apr;87(4):776-81.

  • Chang, HC; Liu, H; Zhang, J; Grifo, J; Krey, LC. “Ooplasnnic factors are responsible for the developmental defects observed when immature cumulus-enclosed mouse oocytes are denuded prior to maturation [Abstract]”. Fertility & Sterility. 2004; 82: S10 (#J0078695)

  • Chang HC, Liu H, Zhang J, Grifo J, Krey LC. (2005) Developmental incompetency of denuded mouse oocytes undergoing maturation in vitro is ooplasmic in nature and is associated with aberrant Oct-4 expression. Human Reproduction, July, Vol. 20, No.7, 1958-1968.

  • Chang, HC; Liu, H; Zhang, J; Grifo, J; Krey, LC. “Ooplasnnic factors are responsible for the developmental defects observed when immature cumulus-enclosed mouse oocytes are denuded prior to maturation [Abstract]”. Fertility & Sterility. 2004; 82: S10 (#J0078695)

  • Liu H, Chang HC, Zhang J, Grifo J, Krey LC. Metaphase II nuclei generated by germinal vesicle transfer in mouse oocytes support embryonic development to term. Human Reproduction, 2003 Sep;18(9):1903-1907.

  • Chang HC, Liu H, Blaszczyk A, Grifo J, Krey LC (2003) Influences of mouse strain and culture media on in vitro maturation and embryogenesis of denuded mouse oocytes. Fertility and Sterility, Vol.80 3S S266. (#J0101655)

  • Liu H, Krey LC, Zhang J, Chang HC, Grifo JA (2002) Germinal vesicle xeno-transfer between mouse and human oocytes: a model to study ooplasmic influences on meiotic division. Fertility and Sterility, September Vol.76 No. 3S O-202.

  • Chang HC, Liu H, Grifo JA, Krey LC (2002) Influences of Gonadotroping stimulation on in vitro maturation and embryogenesis of denuded mouse oocytes. Fertility and Sterility, September Vol.76 No. 3S P-458.

  • Chang HC, Wu MY, Ho HN, Yang YS (1996) Delayed delivery of surviving triplet after fetal reduction and spontaneous abortion. Journal of Formos Medical Association. Nov;95(11):881-4. (original paper)

  • Published at the American Association of Reproductive Medicine (ASRM)

  • Noyes N, Chang HC, Labella P, McCaffrey C, Fino E, Grifo J. (2007 ASRM) Visualization of meiotic spindle predicts usefulness of female gamates in an oocyte cryopreservation program.

  • Chang HC, Grifo J, McCaffrey, Krey LC, Noyes N. (2007 ASRM) Using certain commercially available glass-bottomed dish with paraffin oil impacts the embryonic development of oocytes.

  • Chang HC, Grifo J, Ampeloquio E, LaBella P, Adler A and Krey LC. (2006 ASRM) Oct3A and Oct3B immunostaining patterns in human 3PN zygotes and aneuploid embryos diagnosed by preimplantation genetic diagnosis (PGD): embryonic chromosome status can be independent of developmental competence.

  • Chang HC, Noyes N, Lee TL, Chin A, Krey LC and Grifo JA. (2006 ASRM) Independent and sequential expression of Oct3A and Oct3B transcription factors in human preimplantation embryos.

  • Chang HC, Liu H, Noyes N, Meng L, Krey LC and Grifo J. (2006 ASRM) Down regulatory effects of retinoid signaling on murine and human embryonic Oct-4 gene expression. Liu H, Labella P, Chang HC, Noyes N, Krey LC and Grifo JA. (2006 ASRM) Vitrification influence on the viability of human and mouse oocytes is temperature relevant.

  • Grifo J, Labella P, Licciardi F, Chang HC, Liu H and Noyes N. (2006 ASRM) Clinical results of an oocyte cryopreservation program. Noyes N, Chang HC, Meng L, Liu H, Labella P, Grifo J (2006 ASRM) Presence of meiotic spindle predicts embryo competence following oocyte cryopreservation.

  • Chang HC, Liu H, Zhang J, Grifo J, Krey LC. (2005 SRM) Vitrification of metaphase II oocytes impacts Oct-4 expression during subsequent preimplantation development. Oral presentation in Montreal, 61th Annual Meeting of the American Society for Reproductive Medicine.

  • Chang HC, Liu H, Zhang J, Grifo J, Krey LC. (2004 ASRM) Ooplasmic factors are responsible for the developmental defects observed when immature cumulus-enclosed mouse oocytes are denuded prior to maturation. Oral presentation in Philadelphia, 60th Annual Meeting of the American Society for Reproductive Medicine.

  • Chang HC, Liu H, Blaszczyk A, Grifo JA, Krey LC (2003 ASRM) Influences of mouse strain and culture media on in vitro maturation and embryogenesis of denuded mouse oocytes. Fertility and Sterility, Vol.80 3S S266.

  • Chang HC, Liu H, Grifo J, Krey LC (2002 ASRM) Influences of gonadotropin stimulation on in vitro maturation and embryogenesis of denuded mouse oocytes. Poster presentation in Orlando, 59th Annual Meeting of the American Society for Reproductive Medicine.

  • Liu H, Krey LC, Zhang J, Chang HC, Grifo JA (2002 ASRM) Germinal vesicle xeno-transfer between mouse and human oocytes: a model to study ooplasmic influences on meiotic division. Fertility and Sterility, September 2002 Vol.76 No. 3S O-202. 58th Annual Meeting of the American Society for Reproductive Medicine.